Muramasa follows the story of Kisuke, a fugitive who has lost his memory, including that of a crime that he committed and Momohime, a lithe female ronin possessed by a dark spirit. Gameplay allows players to use the Wii Remote, the Classic controller and the GameCube controller. The game allows players to use two different characters and features three difficulty levels.
Within its first week of release in Japan, Muramasa sold all of its shipped copies and reached the top Japan sales list (known in Japan as Oboromuramasa, literally "Hazy Muramasa").
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